| 发明名称 |
Enhanced death receptor agonists |
| 摘要 |
Methods and compositions for treatment of cancer in a human patient comprising administering a therapeutically effective amount of an Fc-polypeptide agonist of DR5 having high-affinity to FCGR3A. Methods of making the Fc-polypeptides are provided. |
| 申请公布号 |
AU2011252841(B2) |
申请公布日期 |
2014.04.03 |
| 申请号 |
AU20110252841 |
申请日期 |
2011.05.13 |
| 申请人 |
AMGEN INC. |
发明人 |
GRAVES, JONATHAN DAVID;KORDICH, JENNIFER JOY;COTTRELL, SUSAN ELLEN;HUANG, CHANG-PIN |
| 分类号 |
C07K16/28;A61K39/395;A61K45/06;A61P35/00;C12Q1/68 |
主分类号 |
C07K16/28 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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