发明名称 |
PROCESS FOR PRODUCING ESTER COMPOUND |
摘要 |
Compound (1) or a salt that is useful as an intermediate for the production of a medicine, an agrochemical or the like can be produced by a process including the following steps: (A) reacting an aldehyde (2) with nitromethane to produce a nitroaldehyde; (B) reacting the nitroaldehyde with an alcohol to produce a nitroacetal; (C) reducing the nitroacetal to produce an aminoacetal; (D) protecting an amino group in the aminoacetal to produce a protected aminoacetal; (E) treating the protected aminoacetal with an acid and subsequently with a base and then reacting the resultant product with a cyanating agent to produce a nitrile; (F) hydrolyzing the nitrile to produce a protected amino acid; and (G) substituting a group R5 in the protected amino acid by a hydrogen atom and protecting a carboxyl group therein. |
申请公布号 |
US2014094616(A1) |
申请公布日期 |
2014.04.03 |
申请号 |
US201214118004 |
申请日期 |
2012.05.17 |
申请人 |
IKEMOTO TETSUYA;LUTETE LEOPOLD MPAKA;AIKAWA TOSHIAKI;SUMITOMO CHEMICAL COMPANY, LIMITED |
发明人 |
IKEMOTO TETSUYA;LUTETE LEOPOLD MPAKA;AIKAWA TOSHIAKI |
分类号 |
C07D209/52;C07C217/44;C07C223/02;C07D317/16;C07D317/28 |
主分类号 |
C07D209/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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