| 发明名称 |
HUMAN TOLL-LIKE RECEPTOR INHIBITORS AND METHODS OF USE THEREOF |
| 摘要 |
Provided herein are human Toll-like receptor (TLR)-inhibitors and methods for use in individuals having an autoimmune disease or an inflammatory disorder. The TLR inhibitors of the present disclosure are polynucleotides comprising an inhibitory motif for one or more of TLR7, TLR8 and TLR9. |
| 申请公布号 |
CA2886755(A1) |
申请公布日期 |
2014.04.03 |
| 申请号 |
CA20132886755 |
申请日期 |
2013.09.27 |
| 申请人 |
DYNAVAX TECHNOLOGIES CORPORATION |
发明人 |
GUIDUCCI, CRISTIANA;FEARON, KAREN L.;BARRAT, FRANCK |
| 分类号 |
C12N15/117;A61K31/7115;A61K39/39;A61P37/06 |
主分类号 |
C12N15/117 |
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