| 发明名称 |
A GUTLESS ADENOVIRUS VECTOR COMPRISING INDOLEAMINE 2,3-DIOXYGENASE AND ITS USE IN THE TREATMENT OF RENAL DISEASE |
| 摘要 |
<p>A method for treating a renal disease in a subject is disclosed. The method includes administering into a kidney of the subject with an effective amount of a gutless adenoviral vector containing a polynucleotide encoding a therapeutic agent. The gutless adenoviral vector contains the nucleotide sequence of SEQ ID NO:13 or SEQ ID NO:15 and expresses the therapeutic agent in a kidney tissue of the subject.</p> |
| 申请公布号 |
EP2393497(B1) |
申请公布日期 |
2014.04.02 |
| 申请号 |
EP20090839006 |
申请日期 |
2009.02.17 |
| 申请人 |
BIOVEC LLC |
发明人 |
SEHGAL, LAKSHMAN, R.;WONG, JONATHAN |
| 分类号 |
A61K39/235;A61K38/36;A61K38/44;A61K39/00;A61K48/00;A61P13/12;C07K14/745;C12N7/00;C12N15/86 |
主分类号 |
A61K39/235 |
| 代理机构 |
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