发明名称 |
BIOCHEMICAL MARKERS FOR NEURODEGENERATIVE CONDITIONS |
摘要 |
<p>A method of bioassay for the quantification of peptide fragments relevant to neurodegenerative conditions comprising a neo-epitope formed by cleavage of a Tau protein by a secretase such as ADAM10 comprises contacting a blood derived sample with an antibody specific for the neo-epitope and determining the level of binding of said immunological binding partner to peptide fragments in said sample. Neo-epitope containing peptide levels are found to be inversely correlated to cognitive function.</p> |
申请公布号 |
KR20140040243(A) |
申请公布日期 |
2014.04.02 |
申请号 |
KR20147001378 |
申请日期 |
2012.07.04 |
申请人 |
NORDIC BIOSCIENCE A |
发明人 |
BARASCUK NATASHA;KARSDAL MORTEN;HENRIKSEN KIM |
分类号 |
G01N33/68;C12Q1/37;G01N33/53 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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