发明名称 Azaindenoisoquinoline topoisomerase I inhibitors
摘要 The invention described herein pertains to substituted azaindenoisoquinoline compounds, in particular 7-, 8-, 9-, and 10-azaindenoisoquinoline compounds, which are inhibitors of topoisomerase I, processes and intermediates for their syntheses, pharmaceutical compositions of the compounds, and methods of using them in the treatment of cancer.
申请公布号 US8686146(B2) 申请公布日期 2014.04.01
申请号 US201213548579 申请日期 2012.07.13
申请人 CUSHMAN MARK S.;KISELEV EVGENY A.;MORRELL ANDREW E.;PURDUE RESEARCH FOUNDATION 发明人 CUSHMAN MARK S.;KISELEV EVGENY A.;MORRELL ANDREW E.
分类号 C07D471/00;A61K31/44;C07D221/22 主分类号 C07D471/00
代理机构 代理人
主权项
地址