| 发明名称 |
Sphingosine kinase inhibitor prodrugs |
| 摘要 |
The invention relates to prodrugs of hydroxyl-substituted adamantane compounds, pharmaceutical compositions thereof, and methods for inhibiting sphingosine kinase and for treating or preventing hyperproliferative disease, inflammatory disease, or angiogenic disease. |
| 申请公布号 |
US8685936(B2) |
申请公布日期 |
2014.04.01 |
| 申请号 |
US201013255813 |
申请日期 |
2010.03.12 |
| 申请人 |
SMITH CHARLES D.;ZHUANG YAN;MAINES LYNN W.;APOGEE BIOTECHNOLOGY CORPORATION |
发明人 |
SMITH CHARLES D.;ZHUANG YAN;MAINES LYNN W. |
| 分类号 |
A61K31/70;A61K31/27;A61K31/66;C07C269/00;C07F9/02;C07H17/00 |
主分类号 |
A61K31/70 |
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