发明名称 Compositions and methods for reducing the risk of agent-induced liver toxicity
摘要 The present disclosure relates generally to a pharmaceutical compositions and methods of reducing acetaminophen-induced liver toxicity. The disclosure includes pharmaceutical compositions including acetaminophen and one or more components selected from S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof. The disclosure also relates to methods of reducing acetaminophen-induced liver toxicity in a subject by administering or co-administering one or more of S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof, with acetaminophen to a subject.
申请公布号 US8685956(B2) 申请公布日期 2014.04.01
申请号 US201013395736 申请日期 2010.09.16
申请人 LIU HONG-HSING;PELTZ GARY ALLEN;LIAO GUOCHUN;GARROW TIMOTHY ALAN;THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 发明人 LIU HONG-HSING;PELTZ GARY ALLEN;LIAO GUOCHUN;GARROW TIMOTHY ALAN
分类号 A61K31/33 主分类号 A61K31/33
代理机构 代理人
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