| 发明名称 |
BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS |
| 摘要 |
The present invention provides compounds of formula (I)where radical values are as defined in the specification, a pharmaceutical composition containing thereof, process for preparation thereof and use thereof as B-Raf kinase inhibitors, in particular, for the treatment melanoma in mammals such as human. |
| 申请公布号 |
EA019349(B1) |
申请公布日期 |
2014.03.31 |
| 申请号 |
EA20100001680 |
申请日期 |
2009.05.04 |
| 申请人 |
GLAXOSMITHKLINE LLC |
发明人 |
ADAMS JERRY, LEROY;DICKERSON SCOTT, HOWARD;JOHNSON NEIL, W.;KUNTZ KEVIN;PETROV KIMBERLY;RALPH JEFFREY, M.;RHEAULT TARA, RENAE;SCHAAF GREGORY;STELLWAGEN JOHN;TIAN XINRONG;UEHLING DAVID, EDWARD;WATERSON ALEX, GREGORY;WILSON BRIAN;ADJABENG GEORGE;HORNBERGER KEITH |
| 分类号 |
C07D417/04;A61K31/506;A61K31/5377;A61P35/00;C07D413/04;C07D413/14;C07D417/14 |
主分类号 |
C07D417/04 |
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