发明名称 ALKYLSULFONYL-SUBSTITUTED N-(THIAZOLE-2-YL)BENZAMIDES AND USE THEREOF FOR TREATING HEPATITIS C VIRUS INFECTION
摘要 A new class is proposed of alkylsulfonyl-substituted N-(thiazole-2-yl)benzamide and use thereof of general formula (I)or a salt thereof, in which R-Rare, each independently of one another, chosen from H, OH, (C-C)alkylthio, (C-C)alkylsulfonyl, -O-CO-(C-C)alkyl and -O-SO-(C-C)alkyl; and Rand Rare, each independently of one another, chosen from a group comprising H, (C-C)alkylthio, (C-C)alkylsulfonyl and -O-SO-(C-C)alkyl, provided that at least one of R-Ror Ris (C-C)alkylsulfonyl or -O-SO-(C-C)alkyl. These compounds show strong activity against hepatitis virus.
申请公布号 EA019357(B1) 申请公布日期 2014.03.31
申请号 EA20100070182 申请日期 2008.08.01
申请人 ROMARK LABORATORIES L.C. 发明人 SEMPLE J., EDWARD;ROSSIGNOL JEAN-FRANCOIS
分类号 C07D277/46;A61K31/426;A61P31/14;C07D417/12 主分类号 C07D277/46
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