发明名称 Quinolone compound
摘要 The present invention provides a compound represented by the formula (I) wherein X is a hydrogen atom or a fluorine atom; R is a hydrogen atom or alkyl; R1 is (1) cyclopropyl optionally substituted by 1 to 3 halogen atoms or (2) phenyl optionally substituted by 1 to 3 halogen atoms; R2 is alkyl, alkoxy, haloalkoxy, a halogen atom, cyano, etc.; and R3 is 7-oxo-7,8-dihydro-1,8-naphthyridinyl, 3-pyridyl, etc., or a salt thereof. The compound of the present invention has excellent antimicrobial activity against Clostridium difficile and is useful for the prevention or treatment of intestinal infection such as Clostridium difficile-associated diarrhea.
申请公布号 IL230559(D0) 申请公布日期 2014.03.31
申请号 IL20140230559 申请日期 2014.01.20
申请人 OTSUKA PHARMACEUTICAL CO. LTD. 发明人
分类号 C07D 主分类号 C07D
代理机构 代理人
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