(s)-n-((s)-1-cyclohexyl-2-{(s)-2-[4-(4-fluoro-benzoyl)-thiazol-2-yl]-pyrrolidin-1-yl}-2-oxo-ethyl)-2-methylamino-propionamide, pharmaceutical compositions comprising it and its use in the preparation of medicaments for treating cancer
摘要
<p>The present invention is directed to a Smac peptidomimetic of the formula:
or pharmaceutically acceptable salts thereof and use of such compounds as IAP inhibitors for treating proliferative diseases such as cancer, in mammals.</p>