发明名称 |
T-cellereceptorfremvisning |
摘要 |
A proteinaceous particle, for example a bacteriophage, ribosome or cell, displaying on its surface a T-cell receptor (TCR). The displayed TCR is preferably a heterodimer having a non-native disulfide bond between constant domain residues. Such display particles may be used for the creation of diverse TCR libraries for the identification of high affinity TCRs. Several high affinities are disclosed. |
申请公布号 |
DK2048159(T3) |
申请公布日期 |
2014.03.31 |
申请号 |
DK20090001469T |
申请日期 |
2003.10.30 |
申请人 |
IMMUNOCORE LTD.;ADAPTIMMUNE LIMITED |
发明人 |
BOULTER, JONATHAN MICHAEL;JAKOBSEN, BENT KARSTEN;ANDERSEN, TORBEN BENT;MOLLOY, PETER EAMON;LI, YI |
分类号 |
C07K14/705;C12N7/00;C12N15/10 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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