发明名称 Tetrahydrocarboline derivative
摘要 <p>603575 Disclosed herein are compounds of formula (I), wherein the variables are defined in the specification, and the use of said compounds in the treatment of a urinary excretion disorder and/or improving the symptoms thereof. The compounds are disclosed to have ENPP2 inhibitor activity. In one embodiment the compound is cis-4-(2-{ 9-[(2,5-dimethyl-1,3-thiazol-4-yl)methyl]-1,3,4,9-tetrahydro-2H-β-carbolin-2-yl} -2-oxoethyl)cyclohexanecarboxylic acid.</p>
申请公布号 NZ603575(A) 申请公布日期 2014.03.28
申请号 NZ20110603575 申请日期 2011.07.05
申请人 ONO PHARMACEUTICAL CO. LTD. 发明人 OHATA AKIRA;MORIMOTO TAKASHI;NAKATANI SHINGO;SUGIYAMA TETSUYA
分类号 C07D471/04;A61K31/437;A61K31/4375;A61K31/4545;A61K31/497;A61K45/00;A61P11/00;A61P13/00;A61P13/08;A61P17/00;A61P19/02;A61P21/00;A61P29/00;A61P35/00;A61P43/00;C07D471/14 主分类号 C07D471/04
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