发明名称 Proteasome Inhibitors And Methods Of Using The Same
摘要 The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
申请公布号 US2014088042(A1) 申请公布日期 2014.03.27
申请号 US201313949346 申请日期 2013.07.24
申请人 CEPHALON, INC. 发明人 BERNARDINI RAFFAELLA;BERNAREGGI ALBERTO;CASSARA PAOLO G.;CHATTERJEE SANKAR;D'ARASMO GERMANO;DE MUNARI SERGIO;FERRETTI EDMONDO;IQBAL MOHAMED;MENTA ERNESTO;MESSINA MCLAUGHLIN PATRICIA A.;OLIVA AMBROGIO
分类号 A61K31/69;A61K45/06;C07F5/02 主分类号 A61K31/69
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