发明名称 MAMMALIAN CELL SURFACE ANTIGENS; RELATED REAGENTS
摘要 PROBLEM TO BE SOLVED: To provide at least one alternative co-stimulatory molecule, antagonists and agonists useful in modulating a plethora of immune responses.SOLUTION: The present invention provides: substantially pure or recombinant 312C2 proteins or conservatively modified variants thereof; proteins which specifically bind to antibodies generated against previously described proteins; or pure or recombinant 312C2 proteins having specific amino acid sequences respectively in mice and humans.
申请公布号 JP2014054249(A) 申请公布日期 2014.03.27
申请号 JP20130183661 申请日期 2013.09.05
申请人 MERCK SHARP & DOHME CORP 发明人 GORMAN DANIEL M;RANDALL TROY D;ZLOTNIK ALBERT
分类号 C12N15/09;A61K31/7088;A61K31/711;A61K38/00;A61K39/395;A61K48/00;A61P37/02;C07K14/705;C07K14/725;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/0783;C12N5/10;C12N15/12;C12P21/02;C12P21/08;C12Q1/68 主分类号 C12N15/09
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