发明名称 |
MAMMALIAN CELL SURFACE ANTIGENS; RELATED REAGENTS |
摘要 |
PROBLEM TO BE SOLVED: To provide at least one alternative co-stimulatory molecule, antagonists and agonists useful in modulating a plethora of immune responses.SOLUTION: The present invention provides: substantially pure or recombinant 312C2 proteins or conservatively modified variants thereof; proteins which specifically bind to antibodies generated against previously described proteins; or pure or recombinant 312C2 proteins having specific amino acid sequences respectively in mice and humans. |
申请公布号 |
JP2014054249(A) |
申请公布日期 |
2014.03.27 |
申请号 |
JP20130183661 |
申请日期 |
2013.09.05 |
申请人 |
MERCK SHARP & DOHME CORP |
发明人 |
GORMAN DANIEL M;RANDALL TROY D;ZLOTNIK ALBERT |
分类号 |
C12N15/09;A61K31/7088;A61K31/711;A61K38/00;A61K39/395;A61K48/00;A61P37/02;C07K14/705;C07K14/725;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/0783;C12N5/10;C12N15/12;C12P21/02;C12P21/08;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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