发明名称 |
BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES AS APJ RECEPTOR MODULATORS |
摘要 |
The present invention relates to benzoimidazole-carboxylic acid amide compounds of the formula I, in which R', R", R"', R1, R2, R3, R4, R5, R6 and Z are defined as indicated below. The compounds of the formula I are APJ receptor modulators, and are useful for the treatment of diseases associated with increased blood pressure for example. The invention furthermore relates to the use of compounds of the formula I, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them. |
申请公布号 |
WO2014044738(A1) |
申请公布日期 |
2014.03.27 |
申请号 |
WO2013EP69432 |
申请日期 |
2013.09.19 |
申请人 |
SANOFI |
发明人 |
HACHTEL, STEPHANIE;WOHLFART, PAULUS;WESTON, JOHN;MUELLER, MARCO;DEFOSSA, ELISABETH;MERTSCH, KATHARINA;WENG, JIAN-HUI;BINNIE, ROBERT A.;ABDUL-LATIF, FARID;BOCK, WILLIAM JEROME;WALSER, ARMIN |
分类号 |
C07D235/08;A61K31/4184;A61P3/10;A61P9/10;C07D403/06;C07D405/06;C07D409/14;C07D411/06;C07D413/14;C07D417/06;C07D451/04;C07D487/06 |
主分类号 |
C07D235/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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