发明名称 IMIDAZOPYRIDINE COMPOUNDS
摘要 [Problem] An excellent drug for treating or preventing cardiovascular diseases, based on cGMP production enhancing action due to soluble guanylate cyclase activating action, is provided. [Means for Solution] It was found that imidazopyridine compounds having a carbamoyl group at the 3-position and a substituent bonded at the 8-position via an oxygen atom in an imidazo[1,2-a]pyridine skeleton exhibits a cGMP production enhancing action by a potent soluble guanylate cyclase activating action, and is useful as a drug for treating or preventing various soluble guanylate cyclase-related cardiovascular diseases, thereby completing the present invention.
申请公布号 US2014088080(A1) 申请公布日期 2014.03.27
申请号 US201314090074 申请日期 2013.11.26
申请人 ASTELLAS PHARMA INC. 发明人 KOGA YUJI;MAENO KYOICHI;SATO IPPEI;IMAMURA YOSHIMASA;HANAZAWA TAKESHI;IIDA MAIKO;OHNE KAZUHIKO;IMAMURA KENICHIRO;WATANABE TSUBASA;NOZAWA EISUKE;SHIBATA HIROSHI
分类号 C07D471/04;C07D453/02 主分类号 C07D471/04
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