发明名称 |
CARDIAC GLYCOSIDES ARE POTENT INHIBITORS OF INTERFERON-BETA GENE EXPRESSION |
摘要 |
The invention provides for a method of inhibiting interferon-beta gene expression and/or reducing the level of interferon-beta in a cell by contacting the cell with a Na+, Ca2+, or K+ ion-channel modulator. The invention also provides for a method of treating a disease or disorder characterized by elevated interferon beta levels or elevated levels of interferon-beta gene expression. Additionally, the invention provides a method for treating pathogenic or non-pathogenic infections. |
申请公布号 |
US2014088056(A1) |
申请公布日期 |
2014.03.27 |
申请号 |
US201113876795 |
申请日期 |
2011.09.28 |
申请人 |
YE JUNQIANG;CHEN SHUIBING;MANIATIS TOM;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
YE JUNQIANG;CHEN SHUIBING;MANIATIS TOM |
分类号 |
A61K31/585;A61K31/136;A61K31/17;A61K31/407;A61K31/505;A61K31/519 |
主分类号 |
A61K31/585 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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