| 摘要 |
A prostaglandin E composition comprises are substantially free from C1 -C 4 alcohols and include the prostaglandin E compound together with a (C1-C4 )-alkyl (C8 -C2 2) carboxylic ester (e.g., ethyl laurate), an N,N-di(CI-Cs) alkylamino substituted, (C 4-Cis) alkyl (C2-C1 8 ) carboxylic ester and/or a pharmaceutically acceptable addition salt thereof, and optionally, a viscosity enhancing agent such as guar gum. The prostaglandin E composition can be combined with an aqueous alcoholic diluent to form a pharmaceutical composition for topical application to a patient, for example, to treat sexual dysfunction. The prostaglandin E compositions are stable for prolonged periods of storage at room temperature. 5167507 1 (GHMatters) P80706.AU.1 |
