COMPOUNDS WITH (SUBSTITUTED PHENYL)-PROPENAL MOIETY, THEIR DERIVATIVES, BIOLOGICAL ACTIVITY, AND USE THEREOF

摘要

PROBLEM TO BE SOLVED: To provide compounds and compositions including pharmaceuticals and cosmetics useful in treating and preventing many symptoms such as androgen associated symptoms.SOLUTION: The present invention provides compounds having at least one (substituted phenyl)-propenal moiety represented by the specified formula, and compositions containing the compounds. In the formula, R3-R4' are independently selected from the group consisting of -H, -OH, and -OCH3; L is a carbonyl or the like; Z is -H or the like; R1 and R2 are independently -H or the like; and X is a halogen atom such as -F.