发明名称 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE
摘要 PROBLEM TO BE SOLVED: To provide novel 3,7-diamino-10H-phenothiazine compounds useful in: treatment or prophylaxis of a disease caused by aggregation of proteins such as tau proteins (e.g., a neurodegenerative disease such as Alzheimer's disease), skin cancer (e.g., melanoma), a viral, bacterial or protozoal disease (e.g., Hepatitis C, HIV, West Nile Virus, or malaria), and the like; and inactivation of a pathogen in a sample (e.g., a blood or plasma sample).SOLUTION: Provided are compounds represented by the specified formula, and pharmaceutically acceptable salts, solvates and hydrates thereof. [In the formula, R, R, R, R, Rand Rare each independently selected from -H, a Calkyl, a Calkenyl, and a halogenated Calkyl; and HXand HXare each independently a protonic acid.]
申请公布号 JP2014055165(A) 申请公布日期 2014.03.27
申请号 JP20130236080 申请日期 2013.11.14
申请人 WISTA LAB LTD 发明人 WISCHIK CLAUDE MICHEL;RICKARD JANET ELIZABETH;HARRINGTON CHARLES ROBERT;HORSLEY DAVID;STOREY JOHN MERVYN DAVID;MARSHALL COLIN;SINCLAIR JAMES PETER;BADDELEY THOMAS CRAVEN
分类号 C07D279/20;A61K31/5415;A61P1/16;A61P25/00;A61P25/28;A61P31/04;A61P31/12;A61P31/14;A61P31/18;A61P33/02;A61P33/06;A61P35/00 主分类号 C07D279/20
代理机构 代理人
主权项
地址