摘要 |
The present invention is based on a detection method of the BRAF mutations V600E and V600K,and of the PI3Kmutations E542K,E545D,E545K and H1047R, in a sample susceptible of containing one or more of such mutations, based on amplification of the sample with the primers of the present invention. Further, the present invention relates to (i) a kit which comprises, amongst its components, amplification reagents including one or more of the primers of the present invention; (ii) the primers themselves; and (iii) use of the method, kit and primers of above, for the diagnosis/ prognosis of a pathological condition in a patient, particularly, of cancer. |