| 摘要 |
PROBLEM TO BE SOLVED: To solve a problem in which only a small amount of medicine arrives at a site of action, and the medicine may cause a side effect on the healthy tissue of the body on te basis of the distribution thereof.SOLUTION: There is provided a method for producing injectable medicament preparations containing a therapeutically and/or diagnostically effective substance which comprises an active agent, a spacer molecule, and at least one protein-binding molecule. After being added to the body, the therapeutically and/or diagnostically effective substance covalently bonds to the body fluid or tissue constituents via the protein-binding molecule, thus providing a form of transport of the active agent that can be hydrolytically or enzymatically cleaved, according to pH, in the body while releasing the active agent. |
