| 摘要 |
PROBLEM TO BE SOLVED: To provide an orally disintegrating tablet having the excellent characteristics of: (1) being easily producible without requiring a special formulation technique and with general equipment; (2) having a suitable strength so as not to be damaged in the distribution process; (3) having fast disintegration in the oral cavity; (4) having good administration feeling with bitterness and rough feeling being largely reduced; and the like.SOLUTION: An orally disintegrating tablet contains (1) D-mannitol, (2) an active ingredient, (3) one or more kinds of disintegrating agents selected from a group consisting of crospovidone and carmellose, (4) a sucrose fatty acid ester, (5) a binding agent and (6) starch, where the content of D-mannitol in the formulation is 50 wt.% or more, oral disintegration is within 30 seconds, and the absolute hardness is 2.5 N/mm. |
