发明名称 |
METHODS FOR IDENTIFYING ANTIBODIES WITH REDUCED IMMUNOGENICITY |
摘要 |
The disclosure describes methods of identifying a variant of a reference antibody with reduced immunogenicity as compared to the reference antibody. The disclosure further describes variants of a reference anti-TNF-α antibody having reduced immunogenicity as compared to the reference anti-TNF-α reference antibody. |
申请公布号 |
WO2014047222(A2) |
申请公布日期 |
2014.03.27 |
申请号 |
WO2013US60480 |
申请日期 |
2013.09.18 |
申请人 |
ABBVIE BIOTHERAPEUTICS INC. |
发明人 |
HARDING, FIONA A.;RAZO, OLIVIA JENNIFER |
分类号 |
C07K16/24;G01N33/68 |
主分类号 |
C07K16/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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