发明名称 |
MIR-18B FOR USE AS A MARKER OF CANCER PROGRESSION AND TARGET FOR THERAPIES TO TREAT CANCER |
摘要 |
<p>The disclosure provides methods for predicting and/or determining whether a subject has cancer based on the level of expression of miR-18b. The disclosure also provides methods for determining whether a cancer in a subject is progressing or regressing based upon the change of expression levels of miR-18b between two time points. The disclosure further provides methods to treat a subject with a cancer by administering a polynucleotide comprising miR-18b and/or an agent that enhances the expression of miR-18b.</p> |
申请公布号 |
CA2885529(A1) |
申请公布日期 |
2014.03.27 |
申请号 |
CA20132885529 |
申请日期 |
2013.09.19 |
申请人 |
SUTTER WEST BAY HOSPITALS |
发明人 |
KASHANI-SABET, MOHAMMED;DAR, ALTAF A. |
分类号 |
C12Q1/68;C12N15/11;G01N33/574 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|