发明名称 HYDROXYLATED AND METHOXYLATED CYCLOPENTA [D] PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS
摘要 [00452] The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula (I). Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
申请公布号 AU2014201211(A1) 申请公布日期 2014.03.27
申请号 AU20140201211 申请日期 2014.03.05
申请人 GENENTECH, INC.;ARRAY BIOPHARMA INC. 发明人 MITCHELL, IAN S.;BLAKE, JAMES F.;XU, RUI;KALLAN, NICHOLAS C.;XIAO, DENGMING;SPENCER, KEITH LEE;BENCSIK, JOSEF R.;LIANG, JUN;SAFINA, BRIAN S.;ZHANG, BIRONG;CHABOT, CHRISTINE;DO, STEVEN;WALLACE, ELI M.;BANKA, ANNA L.;SCHLACHTER, STEPHEN T.
分类号 C07D239/70;A61K31/517;A61P35/00;C07D401/12;C07D403/04;C07D403/12;C07D407/12;C07D409/12;C07D409/14 主分类号 C07D239/70
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