发明名称 |
NOVEL THERAPEUTICAL TOOLS AND METHODS FOR TREATING BLINDNESS |
摘要 |
The present inventions relates to the use of an isolated nucleic acid molecule comprising a nucleotide sequence coding for a hyperpolarizing light-gated ion channel or pump gene from an archeon or for a light-active fragment of said gene, or the nucleotide sequence complementary to said nucleotide sequence, for treating or ameliorating blindness. The light-gated ion channel or pump gene can be a halorhodopsin gene. |
申请公布号 |
EP2271369(B1) |
申请公布日期 |
2014.03.26 |
申请号 |
EP20090731569 |
申请日期 |
2009.04.16 |
申请人 |
NOVARTIS FORSCHUNGSSTIFTUNG, ZWEIGNIEDERLASSUNG FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH |
发明人 |
BALYA, DAVID;BUSSKAMP, VOLKER;LAGALI, PAMELA;ROSKA, BOTOND |
分类号 |
A61K38/00;A61K38/17;A61K48/00;C07K14/215 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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