发明名称 |
WEST NILE VIRUS VACCINE, AND METHOD FOR PRODUCTION THEREOF |
摘要 |
<p>The present invention provides virus-like particles (VLP) highly secreting or producing signal peptide obtained by altering a signal sequence derived from West Nile virus (WNV), the signal peptide, a WNV VLP secretion expression vector containing a nucleic acid encoding prM protein and E protein, a WNP VLP highly secreting or producing animal cell line harboring the vector, a WNV vaccine containing WNV VLP obtained by the cell line as an active ingredient, and a WNV DNA vaccine containing the ALP secretion expression vector as an active ingredient.</p> |
申请公布号 |
EP2221368(B1) |
申请公布日期 |
2014.03.26 |
申请号 |
EP20080846317 |
申请日期 |
2008.11.07 |
申请人 |
JAPAN AS REPRESENTED BY THE DIRECTOR-GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES;THE RESEARCH FOUNDATION FOR MICROBIAL DISEASES OFOSAKA UNIVERSITY |
发明人 |
KOJIMA, ASATO;TAKAHASHI, HIDEHIRO;ISHIKAWA, TOYOKAZU |
分类号 |
A61K31/711;A61K39/12;C07K14/005 |
主分类号 |
A61K31/711 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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