The present invention provides for isolated anti-human-HER3 antibodies or fragments thereof. More particularly the present invention provides an isolated monoclonal antibody that specifically binds to the extracellular domain of HER-3 and competes for binding to the extracellular domain of human HER-3 with the antibody produced obtainable from hybridoma deposited as CNCM-I-4486. The antibodies described in the present invention are useful for the treatment of cancer.
申请公布号
EP2710040(A1)
申请公布日期
2014.03.26
申请号
EP20120723857
申请日期
2012.05.21
申请人
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE);CENTRE VAL D'AURELLE - PAUL LAMARQUE;UNIVERSITE DE MONTPELLIER 1
