发明名称 7-(1H-PYRAZOL-4-YL)-1,6-NATHTHYRIDINE COMPOUNDS AS SYK INHIBITORS
摘要 The present invention relates to a compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (Syk) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast and/or basophil cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory disease and/or allergic disorders, and in cancer therapy, specifically heme malignancies, chronic spontaneous urticaria and autoimmune conditions.
申请公布号 ZA201207859(B) 申请公布日期 2014.03.26
申请号 ZA20120007859 申请日期 2012.10.18
申请人 GLAXO GROUP LIMITED 发明人 ATKINSON FRANCIS LOUIS;DOUAULT CLEMENT;LIDDLE JOHN;PRESTON ALEXANDER GEORGE STEVEN;BARKER MICHAEL DAVID;GARTON NEIL STUART;PATEL VIPULKUMAR KANTIBHAI;WILSON DAVID MATTHEW
分类号 A61K;A61P;C07D 主分类号 A61K
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