发明名称 METHOD FOR PREDICTING EFFECTIVENESS OF ANGIOGENESIS INHIBITOR
摘要 <p>The purpose of the present invention is to provide a method for predicting the effectiveness of an angiogenesis inhibitor in a subject suffering from a tumor. Provided is a method comprising a step of testing for the presence or absence of an a mutation or loss of expression of B-Raf and PTEN in a sample of tumor tissue from the subject. By using the presence or absence of or a mutation or loss of expression of B-Raf and PTEN as an indicator, this method enables the antitumor effectiveness of the angiogenesis inhibitor to be predicted without administering the angiogenesis inhibitor to the subject.</p>
申请公布号 EP2711433(A1) 申请公布日期 2014.03.26
申请号 EP20120786619 申请日期 2012.05.16
申请人 EISAI R&D MANAGEMENT CO., LTD. 发明人 SEMBA, TARO;NARITA, YUSUKE;MINOSHIMA, YUKINORI;YAMAGUCHI, ATSUMI;ADACHI, YUSUKE;YAMADA, KAZUHIKO;MATSUI, JUNJI;KADOWAKI, TADASHI;TAKAHASHI, KENTARO;FUNAHASHI, YASUHIRO
分类号 C12Q1/68;A61K31/47;A61P35/00;A61P43/00;C12N15/09;G01N33/15;G01N33/50 主分类号 C12Q1/68
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