发明名称 |
TRICYCLIC INDOLE DERIVATIVES AS PBR LIGANDS |
摘要 |
The present invention provides a PET tracer that has improved properties for imaging the peripheral benzodiazepine receptor (PBR) as compared with known such PET tracers. The present invention also provides a precursor compound useful in the preparation of the PET tracer of the invention and methods for the preparation of said precursor compound and said PET tracer. Also provided by the present invention is a radiopharmaceutical composition comprising the PET tracer of the invention. Methods for using the PET tracer and the radiopharmaceutical composition are also provided. |
申请公布号 |
ZA201208067(B) |
申请公布日期 |
2014.03.26 |
申请号 |
ZA20120008067 |
申请日期 |
2012.10.25 |
申请人 |
GE HEALTHCARE LIMITED |
发明人 |
ACHANATH RADHA;FAIRWAY STEVEN MICHAEL;MOKKAPATI UMAMAHESHWAR;PASSMORE JOANNA MARIE;TRIGG WILLIAM JOHN;KADAVILPPARAMPU MOHAMED AFSAL MOHAMMED;BALAJI SRINATH;MANTZILAS DIMITRIOS;O'SHEA DENNIS;SHAN BO;WADSWORTH HARRY JOHN |
分类号 |
A61K;C07D |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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