NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES

摘要

The present invention relates to a compound represented by Formula [I] or a pharmaceutically acceptable salt or ester thereof:
wherein:
X 1 , X 2 , X 3 , and X 4 , which may be identical or different, are each C or N, provided that none to two of X 1 , X 2 , X 3 , and X 4 is/are N;
Y is CH or N;
R 1 , R 1 ', R 2 , R 2 ', R 3 , R 3 ', R 4 , and R 4 ', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like;
R 5 is a hydrogen atom or a methyl group;
R 6 and R 7 , which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like;
R 8 and R 8 ', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like;
R 9 is an aryl group or a heteroaryl group which may be substituted; and
n is an integer from 1 to 3,
and a PLK1 inhibitor or an anticancer agent containing the same.