发明名称 NOVEL SPIROCHROMANONE CARBOXYLIC ACIDS
摘要 <p>The invention relates to a compound of a general formula (I): wherein A represents a linking group; Ar1 represents a group formed from an aromatic ring; R1 and R2 each independently represent a hydrogen atom, a halogen atom, a cyano group, a C2-C6 alkenyl group, a C1-C6 alkoxy group, a halo-C1-C6 alkoxy group, a cyclo-C3-C6 alkyloxy group, a C2-C7 alkanoyl group, a halo-C2-C7 alkanoyl group, a C2-C7 alkoxycarbonyl group, a halo-C2-C7 alkoxycarbonyl group, a cyclo-C3-C6 alkyloxycarbonyl group, an aralkyloxycarbonyl group, a carbamoyl-C1-C6 alkoxy group, a carboxy-C2-C6 alkenyl group, or a group of -Q1-N(Ra)-Q2-Rb; a C1-C6 alkyl group optionally having substituent(s); an aryl or heterocyclic group optionally having substituent(s); or a C1-C6 alkyl group or a C2-C6 alkenyl group having the aryl or heterocyclic group; T and U each independently represent a nitrogen atom or a methine group; and V represents an oxygen atom, a sulfur atom or an imino group. The compound of the invention is useful as therapeutical agents for various ACC-related diseases.</p>
申请公布号 EP2307422(B1) 申请公布日期 2014.03.26
申请号 EP20090773588 申请日期 2009.06.29
申请人 MSD K.K. 发明人 JONA, HIDEKI;SHIBATA, YOSHIHIRO;YAMAKAWA, TAKERU
分类号 C07D491/107;A61K31/438;A61K31/444;A61K31/4545;A61K31/4709;A61P1/16;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P31/00;A61P35/00 主分类号 C07D491/107
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