ENANTIOMERS OF FLUCONAZOLE ANALOGUES CONTAINING THIENO-[2,3-D] PYRIMIDIN-4(3H)-ONE MOIETY AS ANTIFUNGAL AGENTS

摘要

The present invention discloses novel enantiomeric antifungal compounds of Formula (1a) and Formula (1b) containing thieno-[2,3-d]Jpyrimidin-4(3H)-one moiety and pharmaceutically acceptable salts thereof, method of preparing these compounds, the use of these compounds in prevention and treatment of fungal infections, and pharmaceutical preparations containing these compounds.