发明名称 |
A STABLE MICRONISED MONOCLINIC FORM OF ASENAPINE MALEATE AND ITS SYNTHESIS |
摘要 |
A stable micronised monoclinic form of asenapine maleate is described, which comprises 5% by weight or less of orthorhombic form or any other crystalline form of asenapine maleate, wherein the asenapine maleate has a particle size distribution characterised by a d90 equal to or below 40 μm. Processes for preparing the stable micronised monoclinic form of asenapine maleate are also described. Formula (I). |
申请公布号 |
EP2709616(A1) |
申请公布日期 |
2014.03.26 |
申请号 |
EP20120723725 |
申请日期 |
2012.05.18 |
申请人 |
LABORATORIOS LESVI, S.L. |
发明人 |
BERTRAN, AGUSTI;TERRADAS, JOSEP |
分类号 |
A61K31/407;C07D491/04 |
主分类号 |
A61K31/407 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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