发明名称 ADJUVANT FOR TRANSDERMAL OR TRANSMUCOSAL ADMINISTRATION AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME
摘要 It is intended to provide a low molecular weight adjuvant which can be administered safely without inducing skin irritation or the like by transdermal or transmucosal administration and is for enhancing immunogenicity of an antigen efficiently. It can be achieved by an immunostimulant adjuvant containing at least one substance selected from the group consisting of aliphatic alcohols, free fatty acids and fatty acid derivatives but does not contain a substance represented by the following formula. (In the formula, R 3 and R 4 may be combined to form a cyclic ring, and R 1 and R 2 independently represent an alkyl side chain having 1 to 16 carbon atoms.)
申请公布号 EP2123296(A4) 申请公布日期 2014.03.26
申请号 EP20080710659 申请日期 2008.01.31
申请人 HISAMITSU PHARMACEUTICAL CO., INC. 发明人 KUWAHARA, TETSUJI;TOKUMOTO, SEIJI;MATSUDO, TOSHIYUKI
分类号 A61K39/39;A61K9/00;A61K9/70;A61K31/075;A61K31/08;A61K31/095;A61K31/12;A61K31/121;A61K31/125;A61K31/13;A61K31/325;A61K31/327;A61K47/10;A61M37/00;A61N1/04;A61N1/30;A61N1/32 主分类号 A61K39/39
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