发明名称 |
Humanized antibodies that bind to CD19 and their uses |
摘要 |
The present invention relates to humanized antibodies or fragments thereof that bind to human CD19. More specifically, the present invention relates to a humanized antibody or fragment thereof that binds to human CD19 comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO: 27, and/or a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO: 28, and/or a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO: 29; and/or comprising a light chain CDR1 comprising the amino acid sequence of SEQ ID NO: 30, and/or a light chain CDR2 comprising the amino acid sequence of SEQ ID NO: 31 and/or a light chain CDR3 comprising the amino acid sequence of SEQ ID NO: 32. |
申请公布号 |
US8679492(B2) |
申请公布日期 |
2014.03.25 |
申请号 |
US20100710442 |
申请日期 |
2010.02.23 |
申请人 |
BLEIN STANISLAS;SKEGRO DARKO;DEBONNEVILLE CHRISTOPHE;BERTSCHINGER MARTIN;GLENMARK PHARMACEUTICALS S.A. |
发明人 |
BLEIN STANISLAS;SKEGRO DARKO;DEBONNEVILLE CHRISTOPHE;BERTSCHINGER MARTIN |
分类号 |
A61K39/395;A61P35/02;C07K16/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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