| 发明名称 |
IMMUNOCONJUGATES, COMPOSITIONS CONTAINING THEM, AND METHODS OF MAKING AND USE |
| 摘要 |
<p>An immunoconjugate in which a phosphate-prodrugged DNA minor groove binding agent of formula (I), where X is a nucleophilically displaceable leaving group, is conjugated to an antibody or an antigen binding fragment of an antibody, and compounds that can be used for making such immunoconjugates, and uses of such immunoconjugates.</p> |
| 申请公布号 |
KR20140036252(A) |
申请公布日期 |
2014.03.25 |
| 申请号 |
KR20137033963 |
申请日期 |
2012.05.24 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
ZHANG QIAN;GANGWAR SANJEEV;PAN CHIN;DERWIN DANIEL W. |
| 分类号 |
A61K47/48;A61K31/404;A61K39/395;A61P35/00;C07D403/06 |
主分类号 |
A61K47/48 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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