发明名称 |
Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation |
摘要 |
The present invention provides an isolated and substantially purified recombinant human arginase having sufficiently high enzymatic activity and stability to maintain Adequate Arginine Depletion in a patient. The present invention also provides a pharmaceutical composition comprising the modified invention enzyme and method for treatment of diseases using the pharmaceutical composition. |
申请公布号 |
US8679810(B2) |
申请公布日期 |
2014.03.25 |
申请号 |
US20070673601 |
申请日期 |
2007.02.12 |
申请人 |
CHENG NING MAN;LEUNG YUN CHUNG;LO WAI HUNG;BIO-CANCER TREATMENT INTERNATIONAL LIMITED |
发明人 |
CHENG NING MAN;LEUNG YUN CHUNG;LO WAI HUNG |
分类号 |
C12N9/96;C12N15/09;A61K9/08;A61K38/00;A61K38/44;A61K38/46;A61P1/00;A61P35/00;C07H21/04;C12N1/21;C12N9/06;C12N9/14;C12N9/78;C12N9/80;C12N15/55;C12N15/74;C12P21/06;C12R1/125 |
主分类号 |
C12N9/96 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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