发明名称 4-PYRAZOLYL-N-ARYLPYRIMIDIN-2-AMINES AND 4-PYRAZOLYL-N-HETEROARYLPYRIMIDIN-2-AMINES AS INHIBITORS OF JANUS KINASES
摘要 The present invention provides substituted bicyclic heteroaryl compounds, 5 including, for example, 4-pyrazolyl-N-arylpyrimidin-2-amines and 4-pyrazolyl-N-heteroarylpyrimidin-2-amines that modulate the activity of kinases and are useful in the treatment of diseases related to activity of kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.(I)
申请公布号 UA104849(C2) 申请公布日期 2014.03.25
申请号 UA20100007505 申请日期 2008.11.13
申请人 ІНСАЙТ КОРПОРЕЙШН 发明人 Лі Юнь-Лун;Яо Веньцин;Роджерс Джеймс Д.
分类号 C07D401/14;A61K31/506;C07D403/04;C07D403/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14;C07D451/06;C07D471/10;C07D491/107;C07D491/16;C07D498/10 主分类号 C07D401/14
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