发明名称 |
WNT COMPOSITIONS AND METHODS OF USE THEREOF |
摘要 |
Wnt compositions and methods for their use are provided. Compositions of the invention comprise fragments of wnt polypeptides having a desired biological activity, which fragments are referred to herein as "mini-wnts". These compositions and methods find particular use in determining bind to Wnt receptors; inhibiting Wnt signaling in a cell that expresses a Wnt receptor; in delivering a functional moiety to a cell that expresses a Wnt receptor; and as an immunogen for producing Wnt-specific antibodies. |
申请公布号 |
KR20140035337(A) |
申请公布日期 |
2014.03.21 |
申请号 |
KR20137022560 |
申请日期 |
2012.01.26 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
GARCIA KENAN CHRISTOPHER;LEVIN ARON |
分类号 |
A61K38/16;A61K39/39;A61K39/395;C07K14/705 |
主分类号 |
A61K38/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|