发明名称 PYRAZOLO[3,4-c]PYRIDINE COMPOUNDS AND METHODS OF USE.
摘要 Pyrazolo[3,4-c]pyridine compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein R1 and R2 are as defined herein, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
申请公布号 MX2014001239(A) 申请公布日期 2014.03.21
申请号 MX20140001239 申请日期 2012.08.10
申请人 F. HOFFMAN-LA ROCHE AG 发明人 WENDY LEE;XIAOJING WANG;STEVEN DO;ALEKSANDR KOLESNIKOV;VICKIE HSIAO-WEI TSUI;ZHAOYANG WEN
分类号 C07D471/04;A61K31/437;A61P9/00;A61P35/00;A61P37/00 主分类号 C07D471/04
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