| 摘要 |
The invention is a bioabsorbable embolic coil for insertion into a vascular defect. The coil comprises a bioabsorbable material such as a bioabsorbable metal, alloy or polymer, or a combination of any of these. The metal can be Mg, or other bioabsorbable metal. The metal can be electropositive relative to human vasculature such as Mg or Fe. The electropositive metals may recruit endothelial cells to the site of a vascular defect. The recruited endothelial cells can form an endothelial layer of cells that wall off the defect from blood flow in about the same amount of time that the bioabsorbable metal is absorbed into the body. Bioabsorbtion of the embolic material may eliminate the mass effect, and forming an endothelial layer walling off the defect may reduce the risk of recanalization. |
