发明名称 |
DRUG THERAPY FOR CANCER, INCLUDING MULTIPLE MYELOMA |
摘要 |
<p>There is provided a pharmaceutical composition for use in therapy comprising a compound of formula (IA) and a compound of formula (IIA). There is also provided the use of the disclosed pharmaceutical composition in the manufacture of a medicament for treating cancer, including a clonal plasma cell malignancy such as multiple myeloma. The multiple myeloma may be relapsed, refractory or bortezomib resistant multiple myeloma. There is also provided the use of a compound of Formula (IA) in the manufacture of a medicament for treating cancer, including a clonal plasma cell malignancy such as multiple myeloma. The multiple myeloma may be relapsed, refractory or bortezomib resistant multiple myeloma. A preferred compound of formula (IA) is guanabenz and a preferred compound of formula (IIA) is bortezomib.</p> |
申请公布号 |
WO2014042598(A1) |
申请公布日期 |
2014.03.20 |
申请号 |
WO2013SG00403 |
申请日期 |
2013.09.17 |
申请人 |
NATIONAL UNIVERSITY OF SINGAPORE |
发明人 |
ZHOU, WEI;SHENOLIKAR, SHIRISH;TAY, SU LING, ANGELINE |
分类号 |
A61K31/155;A61K31/69;A61P35/00 |
主分类号 |
A61K31/155 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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