发明名称 |
ENDORIBONUCLEASES AND METHODS OF USE THEREOF |
摘要 |
The present disclosure provides variant Cas endoribonucleases, nucleic acids encoding the variant Cas endoribonucleases, and host cells genetically modified with the nucleic acids. The variant Cas endoribonucleases find use in a variety of applications, which are also provided. The present disclosure also provides methods of detecting a specific sequence in a target polyribonucleotide; and methods of regulating production of a target RNA in a eukaryotic cell. |
申请公布号 |
WO2013188638(A3) |
申请公布日期 |
2014.03.20 |
申请号 |
WO2013US45602 |
申请日期 |
2013.06.13 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;DOUDNA, JENNIFER A.;JINEK, MARTIN;STERNBERG, SAMUEL H. |
发明人 |
DOUDNA, JENNIFER A.;JINEK, MARTIN;STERNBERG, SAMUEL H. |
分类号 |
C12N9/22;A61K38/47;C12N9/96 |
主分类号 |
C12N9/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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