发明名称 |
PRODRUGS OF DHODH INHIBITORS AND THEIR USES |
摘要 |
The invention generally relates to Pro-Drugs of dihydroorotate dehydrogenase (DHODH) inhibitors and methods of use thereof. In certain embodiments, the invention provides a DHODH inhibitor compound including a cleavable functional group that increases bioavailability as compared to a form of the DHODH inhibitor without the functional group, rendering the former more suitable for therapeutic use. |
申请公布号 |
US2014080768(A1) |
申请公布日期 |
2014.03.20 |
申请号 |
US201213622606 |
申请日期 |
2012.09.19 |
申请人 |
PALMER ALAN;HUDSON MICHAEL J.;TODD RICHARD;CAMILLERI PATRICK |
发明人 |
PALMER ALAN;HUDSON MICHAEL J.;TODD RICHARD;CAMILLERI PATRICK |
分类号 |
C07D213/74;C07D405/12 |
主分类号 |
C07D213/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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