发明名称 IMIDAZOQUINOLINE AND PYRIMIDINE DERIVATIVES AS POTENTIAL MODULATORS OF VBGF-STIMULATED ANGIOGENIC PROCESSES
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to pharmaceutics and medicine, and concerns using 2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydroimidazo[4,5-c]quinolin-1-yl)phenyl]propionitrile or 8-(6-methoxypyridin-3-yl)-3-methyl-1-(4-piperazin-1-yl-3-trifluoromethylphenyl)-1,3-dihydroimidazol[4,5-c]quinolin-2-one.EFFECT: preparing a pharmaceutical formulation for treating a VBGF-stimulated angiogenic disease, a method of treating a VBGF-stimulated angiogenic disease and using the above compounds for the high-efficacy treatment of the above diseases.5 cl, 4 dwg, 4 ex
申请公布号 RU2509558(C2) 申请公布日期 2014.03.20
申请号 RU20100143455 申请日期 2009.03.24
申请人 NOVARTIS AG 发明人 GARSIJA-EHCHEVERRIA KARLOS
分类号 A61K31/4745;A61K31/4188;A61K31/5375;A61P35/00 主分类号 A61K31/4745
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